Anamorelin

Anamorelin

Catalog Number:
L002368521APE
Mfr. No.:
APE-A3179
Price:
$280
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      • Overview
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          Background

          Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.

      • Properties
        • Categories
          Ghrelin receptor agonist, synthetic, orally active
          Alternative Name
          RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643; 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide
          CAS Number
          249921-19-5
          Molecular Formula
          C31H42N6O3
          Molecular Weight
          546.7
          Purity
          98.00%
          Solubility
          insoluble in H2O; ≥20.52 mg/mL in EtOH; ≥91.4 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          CC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)N3CCCC(C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N

          * For Research Use Only

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