Name: Amylin
Price: 381.00 USD

- Overview
  - Endogenous amylin receptor agonist.
    Amylin (also known as islet amyloid polypeptide, or IAPP) is a centrally acting, neuroendocrine hormone and member of the calcitonin family of peptides, synthesized and cosecreted with insulin in the beta cells of pancreatic islets. Amylin inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. Amylin is a major component of the islet amyloid deposited in the pancreas in type 2 diabetes mellitus and may contribute to beta-cell degeneration.
    
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- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    Islet amyloid polypeptide, IAPP
    
    Molecular Formula
    
    C165H261N51O55S2
    
    Molecular Weight
    
    3903.33
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble to 10 mg/ml in DMSO
    
    Other Properties
    
    Sequence: H-Lys-Cys*-Asn-Thr-Ala-Thr-Cys*-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (disulfide bridge between cysteines 2 and 7),KC*NTATC*ATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2
    Modification: C-terminal amide and a disulfide bridge between cysteines 2 and 7
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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