Name: Amylin (8-37) (human)
Price: 364.00 USD

- Overview
  - Amylin receptor antagonist.
    Amylin (8-37) (human) is a peptide fragment of amylin with the first seven amino acids removed, including the disulphide bridge, that acts as an amylin receptor antagonist. Amylin (8-37) (human) inhibits osteoblast proliferation induced by full-length human amylin and has no agonist activity at amylin receptors. Amylin (8-37) (human) induces formation of polymorphic fibrils containing coiled and laterally-associated sheet structures and is cytotoxic to RINm5F islet -cells in vitro when used at a concentration of 25 M, an effect that is inversely correlated with mature fibril content.
    
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- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    IAPP (8-37), Islet Amyloid Polypeptide (8-37) (human)
    
    Molecular Formula
    
    C138H216N42O45
    
    Molecular Weight
    
    3183.49
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble to 1 mg per ml in water
    
    Other Properties
    
    Sequence: H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2,ATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH
    Modification: C terminal amide
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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