Amikacin disulfate

- Overview
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    Background
    
    Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
- Properties
  - Categories
    
    Semisynthetic aminoglycoside antibiotic
    
    Alternative Name
    
    (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide;sulfuric acid
    
    CAS Number
    
    39831-55-5
    
    Molecular Formula
    
    C22H43N5O13·2H2O4S
    
    Molecular Weight
    
    781.76
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in DMSO; insoluble in EtOH; ≥17.37 mg/mL in H2O
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O
    
    * For Research Use Only