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Overview
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Gal alpha 1-3 Gal beta 1-4 GlcNAc, Truncated N-Glycan trisaccharide containing alpha-gal epitope, Alpha Gal glycan is a linear trisaccharide.
m/z: 546.2 g/mol
The native Alpha Gal glycan is a linear trisaccharide with sequence linkages Gal-alpha(1-3)-Gal-beta(1-4)-GlcNAc. This standard was developed as a positive control when using alpha galactosidase for biopharmaceutical glycoprofiling assays.
2-AA and 2-AB labeled versions of this Alpha Gal standard are also available.
Galactose-alpha-1,3-galactose, commonly known as alpha gal, is a carbohydrate found in mammalian meat products. Approximately 1% of immunoglobulins in humans are specific to alpha-gal, and these antibodies (anti- Gal) cause an allergic reaction. Due to its potential immunogenicity, it is important therefore to screen biopharmaceuticals for alpha-gal. Some drug developers are also investigating the use of anti-Gal for tumour therapies.Please contact us at for specific academic pricing.
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Overview