Name: AF/LE Purified Anti-Mouse TCR γ/δ Monoclonal Antibody
Price: 258.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.
- Properties
  - Host
    
    armenian hamster
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    mouse
    
    Formulation
    
    0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.
    
    Storage
    
    Store at 2~8°C. Do not freeze.
    
    Concentration
    
    0.2 mg/mL
    
    Antigen
    
    TCR-γ/δ; γ/δ TCR (Gene ID:110066,110067)
    
    * For research use only.
- Applications
  - Application
    
    Flow Cytometry; IP; IHC