Name: AF/LE Purified Anti-Mouse CD119 Monoclonal Antibody
Price: 258.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
- Properties
  - Host
    
    rat
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG2a kappa
    
    Reactivity
    
    mouse
    
    Formulation
    
    0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.
    
    Storage
    
    Store at 2~8°C. Do not freeze.
    
    Concentration
    
    0.2 mg/mL
    
    Antigen
    
    Interferon gamma receptor 1; Ifngr1; IFN-gamma-R1; IFN-gamma-R-alpha; CD119 (Gene ID:15979; UniProt:P15261)
    
    * For research use only.
- Applications
  - Application
    
    Flow Cytometry