AF/LE Purified Anti-Mouse CD209b Monoclonal Antibody

AF/LE Purified Anti-Mouse CD209b Monoclonal Antibody

Catalog Number:
A001088134RED
Mfr. No.:
RD20383F
Price:
$300
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

      • Properties
        • Host
          armenian hamster
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          mouse
          Formulation
          0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          CD209 antigen-like protein B; Cd209b; DC-SIGN-related protein 1; DC-SIGNR1; OtB7; CD209; Cd209b (Gene ID:69165; UniProt:Q8CJ91)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry; IHC (frozen); WB

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