AF/LE Purified Anti-Mouse CD132 Monoclonal Antibody

AF/LE Purified Anti-Mouse CD132 Monoclonal Antibody

Catalog Number:
A001088135RED
Mfr. No.:
RD20286F
Price:
$300
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

      • Properties
        • Host
          rat
          Antibody Type
          monoclonal
          Isotype
          IgG2b kappa
          Reactivity
          mouse
          Formulation
          0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          Cytokine receptor common subunit gamma; Il2rg; Interleukin-2 receptor subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64; CD132 (Gene ID:16186; UniProt:P34902)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry; IP

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