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Overview
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Background
TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.
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- Properties
- Applications
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Overview
ADAM17 Rabbit mAb
ADAM17 Rabbit mAb
Catalog Number:
A001550644RED
Mfr. No.:
RDSA67241
Price:
$470
Size:
100μL
Quantity:
Add to Cart: