Acyclovir

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC50 values are 0.85 and 0.86 μM respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfe
- Properties
  - Categories
    
    Antiviral agent
    
    Alternative Name
    
    2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
    
    CAS Number
    
    59277-89-3
    
    Molecular Formula
    
    C8H11N5O3
    
    Molecular Weight
    
    225.21
    
    Appearance
    
    A solid
    
    Purity
    
    99.61%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥11.4 mg/mL in DMSO
    
    Storage
    
    Store at RT
    
    SMILES
    
    C1=NC2=C(N1COCCO)NC(=NC2=O)N
    
    * For Research Use Only
- Reference
  - 1. Guo R, Zhang Y, et al. "DNA methylation enzymes and PRC1 restrict B-cell Epstein-Barr virus oncoprotein expression." Nat Microbiol. 2020;10.1038/s41564-020-0724-y. PMID:32424339