Name: Acetylcysteine
Price: 196.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Acetylcysteine is a derivative of cysteine; an acetyl group that is attached to the nitrogen atom. This compound is sold as a dietary supplement commonly claiming antioxidant and liver protecting effects.
- Properties
  - Categories
    
    Antioxidant; mucolytic agent
    
    Alternative Name
    
    N-acetylcysteine; N-acetyl-L-cysteine; NAC; Acetadote; (2R)-2-acetamido-3-sulfanylpropanoic acid
    
    CAS Number
    
    616-91-1
    
    Molecular Formula
    
    C5H9NO3S
    
    Molecular Weight
    
    163.19
    
    Purity
    
    99.72%
    
    Solubility
    
    ≥44.6 mg/mL in H2O; ≥53.3 mg/mL in EtOH; ≥8.16 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC(=O)NC(CS)C(=O)O
    
    * For Research Use Only
- Reference
  - 1. PIUS REYDERG AGYEMANG. "Profifiling of FDA-Approved and Clinical Trial Drugs Revealed Shared Cytotoxicity And Collateral Sensitivity In Resistant (H69ar) And Non-Resistant (H69) Small Cell Lung Cancer Cells. (Drug Repurposing in Cancer Chemotherapy)." South Dakota State University 2021.
    2. Jing Wu, Yan-Qiu You, et al. "DDX5-targeting fully human monoclonal autoantibody inhibits proliferation and promotes differentiation of acute promyelocytic leukemia cells by increasing ROS production." Cell Death & Disease volume 11, Article number: 552 (2020);20 July 2020. PMID:32690860
    3. Mahnaz Maddah, Mohammad A Mandegar, et al. "Quantifying drug-induced structural toxicity in hepatocytes and cardiomyocytes derived from hiPSCs using a deep learning method." J Pharmacol Toxicol Methods. 2020 Sep;105:106895. PMID:32629158
    4. Wang Z, Chen J, et al. "cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity." J Clin Invest. 2019 Aug 13;130:4850-4862. PMID:31408442
    5. Ye J, Xue M, et al. "Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy." Front Pharmacol. 2019 Jun 19;10:676. PMID:31275148