6xHis-Ube2R1 (UbcH3, Cdc34)

- Overview
  - Ube2R1 (UbcH3) is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2R1 was first discovered during screening for cell cycle regulatory mutations that occur in yeast. While Ube2R1 is able to create diubiquitin chains by itself, it works far more efficiently and effectively with the E3 ligase Skp1 (S- phase kinase- associated protein 1)/cullin/F-box, also known as SCF, to promote substrate polyubiquitination.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    UBC3; UBCH3; UBE2R1; E2-CDC34
    
    Source
    
    Bacterial recombinant
    
    Formulation
    
    20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
    
    Storage
    
    Store at -80°C; avoid multiple freeze-thaw cycles
    
    Concentration
    
    See tube label
    
    Molecular Weight
    
    26.7 kDa
    
    Sequence
    
    NCBI RefSeq: NM_004359
    
    * Research Use Only