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6xHis-Ube2N (6xHis-Ubc13/Uev1a)

6xHis-Ube2N (6xHis-Ubc13/Uev1a)

Catalog Number:
EUCE097573UBP
Mfr. No.:
C3200
Price:
$290
  • Size:
    25 µg
    Quantity:
    Add to Cart:
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      • Overview

        • Ube2N (UbcH13/Uev1a) is a complex that acts as an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Uev1a must interact with Ubc13 because it lacks the active site that other E2s posses. Ube2N has been known to catalyze K63 – linked Ub chains which aides in activation of kinases in NF – kappaB signaling pathway, amongst other tasks.

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      • Properties
        • Protein Name
          Ubc13 (UbcH-ben; MGC8489; MGC131857); Uev1a (Ube2V1; CIR1; UEV1; CROC1; UBE2V; UEV-1; CROC-1)
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          Ubc13 (17.1 kDa), Uev1a (19.3 kDa)
          Sequence
          NCBI RefSeq: NM_003348 (Ubc13); NM_021988 (Uev1a)

          * Research Use Only

    Datasheet
    MSDS

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