6xHis-Ube2M (UbcH12)

6xHis-Ube2M (UbcH12)

Catalog Number:
EUCE097576UBP
Mfr. No.:
C3100
Price:
$290
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • Ube2M is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for conjugation of the Ub-like protein NEDD8 to protein substrates. This E2 is unique from Ube2F in the fact that it does not need to complex with an E3 in order to conjugate the NEDD8 to a Cullin Ring Ligase (CRL), which is a subclass of Ub E3s. The major CRL for Ube2M is cullin-4A.

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      • Properties
        • Protein Name
          UBC12; hUbc12; UBC-RS2
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          20.9 kDa
          Sequence
          NCBI RefSeq: NM_003969

          * Research Use Only

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