6xHis-Ube2G2

- Overview
  - Ube2G2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It has been shown to complex with the E3 ligase called GP78 to catalyze K48 – linked Ub chains. This is an endoplasmic reticulum (ER) associated system to help degrade misfolded ER proteins. Ube2G2 likely interacts with Parkin (an E3 ligase that causes autosomal recessive juvenile Parkinsonism) to ubiquitinate and degrade insoluble Pael receptors.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    UBC7
    
    Source
    
    Bacterial recombinant
    
    Formulation
    
    20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
    
    Storage
    
    Store at -80°C; avoid multiple freeze-thaw cycles
    
    Concentration
    
    See tube label
    
    Molecular Weight
    
    18.6 kDa
    
    Sequence
    
    NCBI RefSeq: NM_003343
    
    * Research Use Only