6xHis-SENP8

- Overview
  - Neural precursor cell expressed developmentally downregulated 8 (Nedd8) is a ubiquitin-like protein. Nedd8 can be conjugated on culin proteins and this modification plays a key role in activation of culin-based E3 ubiquitin ligases. SENP8 (also called NEDP1) is a cystein protease that specifically cleaves the Nedd8 precursor to generate mature Nedd8 and deconjugates neddylated proteins including culins and p53.
    
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- Properties
  - Protein Name
    
    DEN1; NEDP1; PRSC2
    
    Source
    
    Bacterial recombinant
    
    Formulation
    
    20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
    
    Storage
    
    Store at -80°C; avoid multiple freeze-thaw cycles
    
    Concentration
    
    See tube label
    
    Molecular Weight
    
    24.1 kDa
    
    Sequence
    
    NCBI RefSeq: NM_001166340.1
    
    * Research Use Only