Name: 6-SIMA phosphoramidite
Price: 1170.00 USD

- Overview
  - SIMA is a full spectral analog of HEX in all fluorescent applications, but has significantly improved stability. It has a higher quantum yield and molecular extinction than HEX. SIMA is also more versatile in oligo synthesis especially due to improved stability during deprotection and simple purification of labeled oligos
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    SIMA Phosphoramidites
    
    Alternative Name
    
    [(3’,6’-dipivaloyl-2’,7’-diphenyl-4,7-dichlorofluoresceinyl)-6-carboxamidohexyl]-1-O- (2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
    
    Molecular Formula
    
    C58H64Cl2N3O10P
    
    Molecular Weight
    
    1065
    
    Purity
    
    > 95%
    
    Other Properties
    
    Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
    Diluent: Anhydrous Acetonitrile
    Deprotection: No changes needed from standard method recommended by synthesizer manufacturer. SIMA labeled oligos are stable at 55°C in ammonium hydroxide (up to 6-8 hours) and can be deprotected with AMA.
    Stability in Solution: 2-3 days, <90% efficient after 4 days
    
    Storage
    
    Freezer storage, -10 to -30°C, dry.
    
    Note
    
    Store labeled oligo in the dark, either dry or in a neutral aqueous media at -20°C. Do not store crude fluorescently labeled oligonucleotides in ammonia.
    
    * For research use only

6-SIMA phosphoramidite

6-SIMA phosphoramidite

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