6α-methyl-11β-Hydroxyprogesterone

- Overview
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    Background
    
    6α-Methyl-11β-hydroxyprogesterone is a synthetic glucocorticoid which has been used in the treatment of inflammatory eye diseases. 6α-Methyl-11β-hydroxyprogesterone is a corticosteroid with anti-inflammatory properties which has been discontinued in the United States. The structure of 6α-Methyl-11β-hydroxyprogesterone is very similar to progesterone. Neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone [1, 2].
    
    [1] The dictionary of drugs: chemical data: chemical data, structures and bibliographies[M]. Springer, 2014.
    [2] SPAETH G L. Hydroxymethylprogesterone: An anti-inflammatory steroid without apparent effect on intraocular pressure[J]. Archives of Ophthalmology, 1966, 75(6): 783-787.
- Properties
  - Categories
    
    corticosteroid and anti-inflammatory
    
    Alternative Name
    
    NSC 63278,Visudrisone; (6α,11β)-11-hydroxy-6-methyl-pregn-4-ene-3,20-dione
    
    CAS Number
    
    2668-66-8
    
    Molecular Formula
    
    C22H32O3
    
    Molecular Weight
    
    344.5
    
    Appearance
    
    A crystalline solid
    
    Purity
    
    Purity ≥95.00%
    
    Solubility
    
    ≤1mg/ml in ethanol;1mg/ml in methanol;1mg/ml in acetonitrile
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    C[[email protected]@]12[[email protected]](CC[[email protected]@H]2C(C)=O)([H])[[email protected]]3([H])C[[email protected]](C)C4=CC(CC[[email protected]]4(C)[[email protected]@]3([H])[[email protected]@H](O)C1)=O
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

6α-methyl-11β-Hydroxyprogesterone

6α-methyl-11β-Hydroxyprogesterone

Background

Documents

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