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Overview
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4'-Phosphopantetheine is a vital intermediate in the biosynthesis of coenzyme A, acting as the precursor to both coenzyme A and its derivatives. It is synthesized from pantothenate (Vitamin B5) and is essential for the activation of acyl groups in various biochemical pathways, including fatty acid metabolism. 4'-Phosphopantetheine is also a critical component of the acyl carrier protein (ACP), which plays a key role in the synthesis of fatty acids and polyketides (Strauss, 2010; Zhang et al., 2006).
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