Name: 2-Cyanoethyl tetraisopropylphosphorodiamidite
Price: Inquiry

- Overview
  - 2-Cyanoethyl tetraisopropylphosphorodiamidite is widely used for the preparation of modified and unmodified nucleoside phosphoramidites. Nucleoside phosphoramidites are attractive reagents for polymer-supported synthesis of oligonucleotides. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on a protected nucleoside.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Reagents
    
    Alternative Name
    
    Bis(diisopropylamino)(2-cyanoethoxy)phosphine;P-Reagent
    
    CAS Number
    
    102691-36-1
    
    Molecular Formula
    
    C15H32N3OP
    
    Molecular Weight
    
    301.42 g/mol
    
    MDL Number
    
    MFCD00012213
    
    Note
    
    There is a hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Nielsen et al (1986). Application of 2-cyanoethyl N,N,N,N-tetraisopropylphosphorodiamidite for in situ preparation of deoxyribonucleoside phosphoramidites and their use in polymer-supported synthesis of oligodeoxyribonucleotides. Nucleic Acids Research. 14:7391-7403
    Nielsen et al (1987). Improved synthesis of (Pri2 N)2POCH2CH2CN. Nucleic Acids Research 15:3636
    Bannwarth et al (1987). A Simple and Effective Chemical Phosphorylation Procedure for Biomolecules. Helvetica chimica acta. 70:175:186

MSDS

Documents

Specification

We Also Recommend

2-Deoxy-L-adenosine

2-Deoxyguanosine monohydrate

4-Dimethylaminopyridine

Coumarin

$180