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2-Amino (n-PAC) deoxy Adenosine 3'-lcaa CPG 500A

2-Amino (n-PAC) deoxy Adenosine 3'-lcaa CPG 500A

Catalog Number:
NAS1055983CHE
Mfr. No.:
N-9512-05
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      • Overview

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      • Properties
        • Categories
          2-fluoro Purine, 2-Amino Purine, Nebularine, and diaminopurine Amidites and Supports
          Shipping
          This material is sensitive to heat and moisture. It requires the fastest shipment possible.
      • Applications
        • Application Description
          2-Amino-2’-deoxyadenosine (N2,N6-diPAC)-3’-CEP and supports (2,6-diminopurine):

          Oligonucleotides modified with 2,6-diaminopurine display greater duplex stability and specificity compared to corresponding oligonucleotides with adenosine. These oligonucleotides have potential application in the detection of single base mismatches in the target strands.1

          Reference:

          1. Hughesman, C. B.; Turner, R. F. B.; Haynes, C. Nucl.. Acids Sym. Ser. 2008, 52, 245.

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