10-Deacetylbaccatin-III (10-DAB)

- Overview
  - 10-Deacetylbaccatin-III (also known as 10-DAB, 10-Deacetylbaccatin) is an intermediate with anticancer activities. is It is used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the Pacific yew tree Taxus brevifolia as well as other species of the genus Taxus. Due to the low availability of taxol from its natural sources, 10-DAB is used as a raw material for the preparation of taxol and its derivatives. Being easily extracted from the annual cute of the yew leaves, 10-DAB has a very folded chemical structure with the α hydroxyl group hindered at C-13 easily to form a hydrogen bond with the 4α acetyl group.
    
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- Properties
  - Categories
    
    Disease Research Fields
    
    CAS Number
    
    32981-86-5
    
    Molecular Formula
    
    C29H36O10
    
    Molecular Weight
    
    544.59
    
    Purity
    
    ≥98%
    
    Storage
    
    Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
    In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
    
    Shipping
    
    Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
    
    SMILES
    
    CC1=C([C@@H](O)C([C@@]2(C)[C@@]3([H])[C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]2O)=O)C(C)(C)[C@@]([C@H]3OC(C5=CC=CC=C5)=O)(O)C[C@@H]1O
    
    * For research use only

10-Deacetylbaccatin-III (10-DAB)

10-Deacetylbaccatin-III (10-DAB)

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