10-Deacetyl Baccatin III

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Paclitaxel (Taxol) has a unique mode of action involving abnormal polymerization of tubulin and disruption of mitosis.
- Properties
  - CAS Number
    
    32981-86-5
    
    Molecular Formula
    
    C29H36O10
    
    Molecular Weight
    
    544.59
    
    Appearance
    
    White or off-white powder
    
    Solubility
    
    Soluble in methanol. Insoluble in water and ethanol.
    
    Other Properties
    
    Source: Taxus Baccata
    Loss on Drying: ≤3.0%
    Purity Level: ≥98.0%
    
    Storage
    
    2-8 °C
    
    * For research use only
- Applications
  - Application Description
    
    Plant Biology Applications: Taxus cell culture may be an alternate source of Paclitaxel, and significantly increased amounts of Paclitaxel were observed after exposure to methyl jasmonate (Yukimune et al, 1996).
    
    Cancer Applications: 10-Deacetyl Baccatin III is commonly used as an intermediate in the synthesis of paclitaxel (Taxol), an anti-cancer drug.