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Overview
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Calculated MW: 31kDa/53kDa
Observed MW: 53KDaPlease contact us at for specific academic pricing.
Background
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
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