Ziprasidone hydrochloride monohydrate

Ziprasidone hydrochloride monohydrate

Catalog Number:
L002368941APE
Mfr. No.:
APE-A3953
Price:
$260
  • Size:
    100mg
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its most potent action is antagonism of 5-HT2A receptors, where its affinity is an order of magnitude greater than that observed for dopamine D2 sites. Additionally, Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine. Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.

      • Properties
        • Categories
          5-HT (serotonin)/dopamine receptor antagonist
          Alternative Name
          CP 88059;CP-88059;CP88059; 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrate;hydrochloride
          CAS Number
          138982-67-9
          Molecular Formula
          C21H24Cl2N4O2S
          Molecular Weight
          467.41
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in H2O; insoluble in EtOH; ≥11.69 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl

          * For Research Use Only

    We Also Recommend

    ZM323881

    $349

    Note: If you don't receive our verification email, do the following:

    Copyright © Amerigo Scientific. All rights reserved.