Zerumbone

Zerumbone

Catalog Number:
FC01366340APE
Mfr. No.:
APE-B8317
Price:
$159
  • Size:
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger),which exhibits antitumor activity[1].Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts.

          [1]Kamalidehghan B, Ahmadipour F, Noordin M I. DNA Fragmentation Is Not Associated with Apoptosis in Zerumbone-induced HepG2 Cells[J]. Iranian Biomedical Journal, 2012, 16(4):226.

      • Properties
        • Categories
          Zerumbone
          Alternative Name
          (2Z,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trienone
          CAS Number
          471-05-6
          Molecular Formula
          C15H22O
          Molecular Weight
          218.33
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in H2O; ≥44.4 mg/mL in EtOH; ≥81.4 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          C/C1=C/CC/C(C)=C/CC(C)(C)/C=C/C1=O

          * For Research Use Only

    We Also Recommend

    FX1

    $220

    HDM201

    $533

    VAS2870

    $274

    Note: If you don't receive our verification email, do the following:

    Copyright © Amerigo Scientific. All rights reserved.