Name: YBX1 Polyclonal Antibody (0.6 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: NP004550
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthetic peptide of human YBX1
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.6 mg/mL
  
  Antigen
  
  BP 8, CBF-A, CCAAT binding transcription factor I subunit A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, DBPB, DNA binding protein B, DNA-binding protein B, EFI-A, Enhancer factor I subunit A, MDR NF1, MGC104858, MGC110976, MGC117250, NSEP 1, NSEP1, Nuclease sensitive element binding protein 1, Nuclease-sensitive element-binding protein 1, p50, Q15905, Y-box binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YB 1, YB-1, YBOX1, YBX 1, ybx1 (UniProt:P67809)
  
  * For reference only.

Applications

Application

IHC; ELISA

Application	Dilutions
IHC	1:30-1:150
ELISA	1:5000-1:10000

YBX1 Polyclonal Antibody (0.6 mg/mL) for IHC, ELISA

YBX1 Polyclonal Antibody (0.6 mg/mL) for IHC, ELISA

Background

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