Vindoline

- Overview
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    Background
    
    Vindoline is a monomeric vinca-alkaloid,forms lower portion of the lead anti-tumor agents,vinblastine and vincristine. Vindoline exhibits reciprocal cross-resistance to vincristine and vinblastine.
- Properties
  - Categories
    
    Monomeric vinca-alkaloid
    
    Alternative Name
    
    Vindoline free base;Bufexamacum; aspidospermidine-3-carboxylicacid,4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-me;thoxy-1-methyl-,methylester,(2-beta,3-beta,4-beta,5-alpha,12-beta,19-alpha); (3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
    
    CAS Number
    
    2182-14-1
    
    Molecular Formula
    
    C25H32N2O6
    
    Molecular Weight
    
    456.53
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    ≥45.7 mg/mL in DMSO; insoluble in H2O; ≥10.08 mg/mL in EtOH with ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C([[email protected]@]1([[email protected]]2([H])N(C([H])([H])[H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])[[email protected]]24[[email protected]@](C(C([H])([H])C([H])([H])[H])(C([H])=C([H])C5([H])[H])[[email protected]@]1([H])OC(C([H])([H])[H])=O)([H])N5C([H])([H])C4([H])[H])O[H])OC([H])([H])[H]
    
    * For Research Use Only