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Vildagliptin

Vildagliptin

Catalog Number:
P004517011LIF
Mfr. No.:
PEPTIDE-PI-230
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  • Size:
    10mg
    Quantity:
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      • Overview

        • Dipeptidyl peptidase IV (DPP-IV) inhibitor.
          Vildagliptin, also known as LAF237, is a potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin inhibits the inactivation of glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP) by DPP-IV, allowing GLP-1 and GIP to potentiate the secretion of insulin and suppress glucagon release in the pancreas. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity in type 2 diabetes.

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      • Properties
        • Categories
          Small Molecules
          Alternative Name
          LAF237
          Molecular Formula
          C17H25N3O2
          Molecular Weight
          303.4
          Appearance
          White solid
          Purity
          98% by TLC
          Solubility
          Soluble in water
          Other Properties
          Sequence: 1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile,1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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