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Overview
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Veratridine (3-Veratroylveracevine) is naturally occuring steroidal
alkaloid found in plants of the lily family, specifically the genera
Veratrum and Schoenocaulon. Upon absorption through the skin or mucous
membranes, it acts as a neurotoxin by binding to and preventing the
inactivation of voltage-gated sodium ion channels in heart, nerve, and
skeletal muscle cell membranes. Veratridine increases nerve excitability
and intracellular Ca²⁺ concentrations. Veratridine is a sodium channel agonist that inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM.Please contact us at for specific academic pricing.
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- Properties
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Overview