Name: VEGF Baculovirus Recombinant Protein
Price: Inquiry

- Overview
  - Baculovirus cells. VEGF produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 197 amino acids (1-191 a.a.) and having a molecular mass of 23.1 kDa. VEGF is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/ macrophagemigration, neurons, cancer cells, kidney epithelial cells ). VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesisand cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.
    
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- Properties
  - Protein Name
    
    Vascular Endothelial Growth Factor A, VEGF, Vascular PermeabilityFactor, MVCD1, VPF, Vascular Endothelial Growth Factor, VEGF-A, Vascularendothelial growth factor A.
    
    Source
    
    Sf9 cells
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    VEGF protein solution (0.25mg/ml) contains Phosphate buffered saline (pH7.4), 10% glycerol, 1mM DTT and 0.1mM PMSF.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

VEGF Baculovirus Recombinant Protein

VEGF Baculovirus Recombinant Protein

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