VAL-083

VAL-083

Catalog Number:
FC01364915APE
Mfr. No.:
APE-A3902
Price:
$633
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      • Overview
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          Background

          VAL-083 is a bi-functional alkylating agent, with potential antitumor activity. VAL-083 can cross the blood brain barrier and appears to be selective for tumor cells. VAL-083 alkylates and crosslinks DNA which ultimately inhibit the proliferation of cancer cells. VAL-083 does not show cross-resistance to other conventional chemotherapeutic agents. The half-life of VAL-083 in the brain is long. VAL-083 has been assessed in multiple studies as chemotherapy in the treatment of newly diagnosed and recurrent brain tumors.

          Reference:http://www. delmarpharma.com/product_development_programs/val083/

      • Properties
        • Categories
          Bi-functional alkylating agent
          Alternative Name
          Dianhydrodulcitol;Dianhydrogalactitol;VAL083;VAL 083; (1S,2R)-1-[(2S)-oxiran-2-yl]-2-[(2R)-oxiran-2-yl]ethane-1,2-diol
          CAS Number
          23261-20-3
          Molecular Formula
          C6H10O4
          Molecular Weight
          146.14
          Purity
          98.00%
          Solubility
          Soluble in DMSO
          Storage
          Store at -20°C
          SMILES
          C1C(O1)C(C(C2CO2)O)O

          * For Research Use Only

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