Ustekinumab Biosimilar - Research Grade, Low Endotoxin

Ustekinumab Biosimilar - Research Grade, Low Endotoxin

Catalog Number:
A001437382ICH
Mfr. No.:
ICH4034
Price:
$560
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      • Overview
        • Specificity: Detects human IL-12 and IL-23. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ustekinumab.
          Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
          Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method

          Please contact us at for specific academic pricing.

          Background

          Ustekinumab is a human IgG1κ monoclonal antibody against the p40 subunit of the IL-12 and IL-23 cytokines. Using DNA recombinant technology, ustekinumab is produced in a well characterized recombinant cell line and is purified using standard bio-processing technology. The manufacturing process contains steps for the clearance of viruses. Ustekinumab is comprised of 1326 amino acids and has an estimated molecular mass that ranges from 148,079 to 149,690 Daltons.

      • Properties
        • Host
          humanized
          Isotype
          IgG1 kappa
          Reactivity
          human
          Purification
          >95% by SDS-PAGE and HPLC
          Formulation
          Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
          Storage
          Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 - 5.0 mg/ml
          Antigen

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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