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Overview
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Specificity: Detects human CD137. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Urelumab.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Isotype Control: Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL methodPlease contact us at for specific academic pricing.
Background
RUO urelumab is a humanized agonistic monoclonal antibody targeting 4-1BB with potential immunostimulatory and antineoplastic activities. Urelumab specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. .
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- Properties
- Applications
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Overview