Uhrf2 Polyclonal Antibody

Uhrf2 Polyclonal Antibody

Catalog Number:
A001509110RED
Mfr. No.:
RD266118A
Price:
$347
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      • Overview
        • Calculated MW: 24 kDa/57 kDa/90 kDa
          Observed MW: 90 kDa

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          Background

          This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          mouse; rat
          Immunogen
          Recombinant fusion protein of mouse Uhrf2 (NP_659122.2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          UHRF2, NIRF, RNF107, TDRD23, URF2, Uhrf2 (Gene ID:109113; UniProt:Q7TMI3)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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