Ugo Basile Rota-Rod

Ugo Basile Rota-Rod

Catalog Number:
LARE530865STO
Mfr. No.:
STO-57624/25/25F/26/24-2/25-1/24-3/24-4
Price:
$9,793
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      • Overview
        • The first Rota-Rod was made commercially available from Ugo Basile many years ago. Since then, thousands of papers have been published and the "Rota-Rod" technique (originated by a 1957 paper of N.W Dunham and T.S Miya) has proved to be of great value in research involving screening of drugs which are potentially active on motory coordination.

          Feature:
          · Speed adjustable in the range
          · 3-80 RPM, in steps of 1 RPM
          · Constant speed, ramp (accelerat­ing), multi-step ramp
          · New trip boxes
          · Embedded USB memory stick
          · Brand new Software

          Benefit:
          · Useful in a variety of tests
          · Extreme versatility
          · To enclose the animals, stainless-steel to ease sterilization
          · Does not required connection to PC (software included) to store and transfer data
          · User friendly, included as stan­dard, enables setting up the experiment and managing the results from PC or 4"3 touch-screen

          Rota-Rod Complex Wheel

          The complex wheel add-on for our Mouse Rota-Rod (57624-2) and Rat Rota-Rod (57625-1) introduce an additional complexity element for the animal
          to be tested.

          This Rota-Rod accessory was developed in conjunction with Prof. Bellesi from the University of Camerino (Italy). The complex wheel is designed in a way that the animal does not have a uniform surface to walk on but rather a number of horizontal bars (rungs) that can be increased in number and positioned in a symmetrical or uneven position to vary the test complexity.

          The objective of the complex wheel and what the first publications show is that sensitivity of the test is increased, allowing to detect even the smallest alterations in
          motor deficits.

          The test has been developed for rats (57625-1) but a version for mice (57624-2) is also available and in course of validation.

          · Easy use, easy care, precision data
          · Easy to operate and monitor experiments using touchscreen.
          · Software included with every RotaRod enables protocols to be defined in advance. This can be uploaded to the RotaRod for accuracy, efficiency and repeatability. Avoids making any data entry errors during the experiment runtime.
          · Records time the mouse stays on the rotating rod as well as time (latency) of fall. Select and customize speeds (from 3 - 80 RPM in steps of 1 RPM), acceleration and deceleration steps.
          · Records fall time latency for up to 5 mice simultaneously. Section width is a comfortable 5.7cm. Low fall height is 16cm allowing a soft landing into an individual box, preventing any harm to the mouse.
          · Machined cylinders provide horizontal ridges for sufficient grip.
          · Saves experimental settings with recorded values. Customizable layout with drag and drop columns. Presents results in a convenient tree-like structure. Enables users to add information before or after each test. Export settings and recorded data as text, spreadsheet or pdf files.
          · Enables remote diagnosis and internet access – data can be saved to the cloud via Dropbox, OneDrive, Google Drive etc.
          · Surprisingly quiet operation for reduced stress.
          · Removable stainless-steel boxes facilitate cleaning and prevent mice from escaping when they fall from the rod.

          Please contact us at for specific academic pricing.

          Background

          Current model is the result of over 50 years of expertise and product reliability. After building and naming the original commercial RotaRod, we have retained a strong leadership position through continuous improvement and innovation.
          Assesses motor coordination by the duration (latency) that a mouse stays on the rod as a function of drum speed.
          Range from 3 to 80 RPM ideal for drug screening to assess any side effects on motor coordination including balance and fatigue.
          Slower speeds suited to motor neuron disease or brain injury studies.
          More than 5000 citations of our RotaRod models in published papers.

      • Properties
        • Other Properties
          Speed: Adjustable in the range 3-80 RPM, in steps of 1 RPM
          Mode: Forward rotation, Reverse rotation, Ramp (Increasing RPM), Alternated Rotation, Personalized
          Start/Stop: From the touch-screen
          Detection: Magnetic sensor
          Results: Time Elapsed, Revolutions, Distance, Speed, Mode for each lane
          Data Acquisition: Via dedicated X-PAD software or .csv file for PC.
          Data Portability: By USB flash drive
          TTL Output: Plate Status, Rotating Direction, Speed
          Data Out: exported to .csv
          Data In: exported to .csv, protocol, ramp
          Power Requirement: Universal input 100-240 VAC, 50-60Hz, 40W max.

          * For animal research only and not intended for human use.

      • Applications
        • Application Description
          Assesses motor coordination, especially for drug screening or motor impairment studies.

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