UBXN1 Polyclonal Antibody

UBXN1 Polyclonal Antibody

Catalog Number:
A001506737RED
Mfr. No.:
RD218676A
Price:
$253
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      • Overview
        • Calculated MW: 33 kDa
          Observed MW: Refer to figures
          Gene Accession: BC001372

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          Background

          Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Full length fusion protein
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.2 mg/mL
          Antigen
          2B28, 4930455J02Rik, D19Ertd721e, MGC124706, MGC6696, mY33K, Protein 2B28, RGD1309471, SAKS1, SAPK substrate protein 1, T25529, UBA/UBX 33.3 kDa protein, UBX domain containing protein 1, UBX domain protein 1, UBXD10, UBXN1 (UniProt:Q04323)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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