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Overview
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Calculated MW: 46kDa/49kDa/85kDa
Observed MW: 50kDaPlease contact us at for specific academic pricing.
Background
This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome.
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