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Overview
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Calculated MW: 32 kDa/33 kDa/38 kDa
Observed MW: 37 kDaPlease contact us at for specific academic pricing.
Background
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.
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