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Overview
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Real Time Amplification kit test for detection of Toxoplasma gondii
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Background
Toxoplasmosis is caused by infection with Toxoplasma gondii, an obligate intracellular parasite. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. In most immunocompetent individuals, primary or chronic (latent) T gondii infection is asymptomatic. A small percentage of these patients eventually develop chorioretinitis, lymphadenitis, or, rarely, myocarditis and polymyo-sitis. However, certain individuals are at high risk for severe or life-threatening toxoplasmosis. Individuals at risk for toxoplasmosis include fetuses, newborns, and immunologically impaired patients. Congenital toxoplasmosis is usually a subclinical infection. Among immunodefi cient individuals, toxoplasmosis most often occurs in those with defects of T-cell mediated immunity, such as those with hematologic malignancies, bone marrow and solid organ transplants, or AIDS.
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Overview