TNF-α Polyclonal Antibody (1 mg/mL) for IHC, IF

TNF-α Polyclonal Antibody (1 mg/mL) for IHC, IF

Catalog Number:
A001510904RED
Mfr. No.:
RD86737A
Price:
$416
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      • Overview
        • Calculated MW: 564kDa/565kDa
          Observed MW: 564KDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human TNF
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% proclin300,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          TNF, DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F, TNF alpha (Gene ID:7124; UniProt:P01375)

          * For reference only.

      • Applications
        • Application
          IHC; IF
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200
          IF 1:50-1:200

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