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Overview
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Tilmicosin is a semisynthetic macrolide antibiotic that is slightly soluble in water.
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Background
Macrolide antibiotics inhibit bacterial growth by targeting the 50S ribosomal subunit preventing peptide bond formation and translocation during protein synthesis. Resistance to tilmicosin is commonly attributed to mutations in 50S rRNA preventing tilmicosin binding allowing the cell to synthesize proteins free of error.
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- Properties
- Applications
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Overview