Name: TGF beta 1 Antibody, 0.99 mg/ml
Price: 180.00 USD

Overview
- Sensitivity: Endogenous
  Target name: TGF beta 1
  Area: Angiogenesis
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
Properties
- Host
  
  Rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  Human, Mouse, Rat
  
  Clone
  
  pAb
  
  Immunogen
  
  Synthetic peptide / encompassing a sequence within the C-terminus region.
  
  Storage
  
  Store at +4°C for short term storage. Long time storage is recommended at -20°C
  100mM Tris Glycine, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
  
  Molecular Weight
  
  12, 33-60
  
  * For research use only.