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Teduglutide Acetate

Teduglutide Acetate

Catalog Number:
P004441096INV
Mfr. No.:
V34647
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      • Overview

        • Teduglutide Acetate (Gattex; Revestive) is a polypeptide composed of 33-amino acids. It is a glucagon-like peptide-2 (GLP-2) analog that has been approved as an orphan drug for use in the treatment of SBS-short bowel syndrome. Teduglutide works by promoting mucosal growth and possibly restoring gastric emptying and secretion. Teduglutide differs from naturally occurring GLP-2 by a single amino acid: an alanine replaced by a glycine, which blocks breaking down of the molecule by dipeptidyl peptidase and increases the half-life from 7 minutes (GLP-2) to about 2 hours, while retaining its biological activity.

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      • Properties
        • Categories
          Peptides
          CAS Number
          287714-30-1
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

          * For research use only

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