Tautomycetin

Tautomycetin

Catalog Number:
L002372120APE
Mfr. No.:
APE-B7009
Price:
$877
  • Size:
    50ug
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Tautomycetin is a potent, selective inhibitor of PP1, with IC50 values being 1.6 nM and 62 nM for the PP1 and PP2A subtypes, respectively. PP1, one of four major protein serine/threonine phosphatases (PPs), plays an important role in regulation of many cellular events such as transcription, translation, cell division, muscle contraction, glycogen synthesis, and neuronal signaling. Compared with over 40 species of natural phosphatase inhibitors reported, tautomycetin is the most specific PP1 inhibitor, which can be served as a novel powerful tool to elucidate the physiological roles of PP1 in a variety of biological events.

      • Properties
        • Alternative Name
          (S)-(2S,3S,4R,7S,8R,11R,13R,Z)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl 3-hydroxy-3-(4-methyl-2,5-dioxo-2,5-dihydrofuran-3-yl)propanoate
          CAS Number
          119757-73-2
          Molecular Formula
          C33H50O10
          Molecular Weight
          606.75
          Appearance
          Colourless liquid
          Purity
          98.00%
          Solubility
          Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml)
          Storage
          Desiccate at -20°C

          * For Research Use Only

    Note: If you don't receive our verification email, do the following:

    Copyright © Amerigo Scientific. All rights reserved.