Name: Tau(Phospho-Ser404) Antibody
Price: 483.00 USD

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Peptide sequence around phosphorylation site of serine 404 (D-T-S(p)-P-R) derived from Human Tau.
  
  Purification
  
  Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  
  Storage
  
  Store at -20°C. Avoid freeze / thaw cycles.
  
  Concentration
  
  1.0 mg/mL
  
  Antigen
  
  MAPT;MTAPT;MTBT1;Neurofibrillary tangle protein;PHF-tau (Gene ID:4137; UniProt:P10636)
  
  * This product is for Research Use Only.

Applications

Application

WB; IHC; IF

Application	Dilutions
WB	1:500-1:1000
IHC	1:50-1:100
IF	1:100-1:200

Tau(Phospho-Ser404) Antibody

Tau(Phospho-Ser404) Antibody

Background

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