Tanshinone IIA

- Overview
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    Background
    
    Major tanshinone isolated from Salvia miltiorrhiza. Inhibits NF-κB and AP-1 DNA binding. Exhibits cytotoxic activity in a number of different cancer cells. Inhibits β-amyloid aggregation and protects PC12 cells from β-amyloid-induced apoptosis. Displays antioxidant and anti-inflammatory properties.
- Properties
  - Categories
    
    Antioxidant and anti-inflammatory reagent
    
    Alternative Name
    
    1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
    
    CAS Number
    
    568-72-9
    
    Molecular Formula
    
    C19H18O3
    
    Molecular Weight
    
    294.34
    
    Appearance
    
    A solid
    
    Purity
    
    99.35%
    
    Solubility
    
    insoluble in EtOH; insoluble in H2O; ≥3.42 mg/mL in DMSO
    
    Storage
    
    Store at RT
    
    SMILES
    
    CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
    
    * For Research Use Only