Name: Streptokinase Recombinant Protein
Price: Inquiry

- Overview
  - Streptokinase Recombinant produced in E. Coli is a non-glycosylated polypeptide chain containing 414 amino acids and having a molecular weight of 47.3kDa. The Streptokinase is purified by proprietary chromatographic techniques. Streptokinase is an extracellular metallo-enzymeproduced by beta-haemolytic streptococcusand is used as an effective and cheap clot-dissolving medicationin some cases of myocardial infarction(heart attack) and pulmonary embolism. It belongs to a group of medications known as fibrinolytics, and works by activating plasminogenthrough cleavage to produce plasmin.
    
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- Properties
  - Protein Name
    
    Streptokinase, SK.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
    
    Formulation
    
    Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4.
    
    Storage
    
    Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Streptokinase should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
    
    Activity
    
    Biological Activity measured by the ability of fibrin lysis in agarose plate was found to be 80000U/mg.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    It is recommended to reconstitute the lyophilized Streptokinase in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The specific biological activity measured by the ability of fibrin lysis in agarose plate was found to be 80000U/mg.

Streptokinase Recombinant Protein

Streptokinase Recombinant Protein

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