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Overview
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STYX Human Recombinant produced in E. coli is a single polypeptide chain containing 221 amino acids (26-223) and having a molecular mass of 25.0kDa. STYX is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. STYX is a member of the protein-tyrosine phosphatase family. STYX has a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase. Nevertheless, the binding pocket is adequately preserved to bind phosphorylated substrates, and possibly protect them from phosphatases. STYX takes part in spermiogenesis.
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Overview